Nicomp 380 激光粒度仪系列

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Nicomp 380 DLS 纳米激光粒度仪

  • Dynamic Light Scattering


    The   Nicomp 380 Submicron Particle Size Analyzer uses the principle of    Dynamic Light Scattering (DLS) to obtain the partcile size distribution    of colloidal systems whose sizes range from 0.5 nanomters to 6 microns.   DLS works by illuminating a group of particles in suspension with a   focused laser beam which gives rise to many scattered light waves.   These    waves interfere with each other and produce a net scattered intensity    that fluctuates as a function of time at some distant detector.    Diffusion, or Brownian motion, of the particles causes random   variations in the phases of the individual waves, resulting in a   fluctuating light     intensity. The particle size distribution can be obtained by   analyzing the time behavior of these fluctuations using an   autocorrelator. The  autocorrelation function for a single uniform size   distribution is a    decaying exponential function where particle diffusivity is easily    obtained from the decay time. Finally the particle radius can easily be   calculated using the Stokes-Einstein relationship.

    In   general most samples are not uniform instead they are quite often    polydisperse, having a range of particle sizes. The autocorrelation   function then consists of a combination of decaying exponential   functions, each having a different decay time and the analysis of the   autocorrelation function is no longer quite simple. The instrument using   varying deconvolution algorithms must invert the raw data in order to   arrive at the best estimate of the true particle size distribution. The   Nicomp excels at characterizing these difficult particle size   distributions by utilizing a group of unique deconvolution algorithms   ranging from a simple Gaussian approximation to a proprietary high   resolution multi-modal deconvolution analyses called the “Nicomp Distribution".

    Some   of the unique features found on Gaussian analysis mode is a baseline   adjust parameter which provides aggregate compensation that excedes the   sensitivity found on most other instruments which employ a dust or dirt   factor. The Gaussian analysis mode also allows for the user to specify a   solid or vesicle weighting mode for analysing thin walled colloidal   systems like liposomes. The Nicomp Analysis Mode is a proprietary    high-resolution deconvolution algorithm that was first introduced over    25 years ago. It has historically proven its ability to accurately   analyze even the most difficult closely spaced bimodals (e.g. 2:1 apart)   and even certain trimodal distributions. This is extremely useful in   finding the native peak of the aggregate distribution.

    The   standard Nicomp 380 is equipped with a 12 mW laser diode and PMT    detector with an optical fiber set to 90°. Sample is introduced with    drop-in cells.

    The 380 is the only Dynamic Light Scattering Instrument designed using a    modular approach. Its capabilities may be enhanced by adding one or more   modules:


    This   patented module eliminates the need for manual dilution of concentrated   sample. Autodilution makes particle size analysis quick and easy, with    no training required. Results are highly reproducible.

    380/HPLD High Power Laser Diodes

    PSS   offers an array of high power laser diodes to meet the needs of our    most demanding applications. Higher power lasers are needed to extend    the lower limit of our instrument by providing adequate scattering from      small particles. They are also useful when measuring large   particles  such as dextrans, which yield insufficient scattering   intensity because    of index of refraction properties. The result is a more versatile   instrument, ideal for sizing microemulsions, surfactant micelles,   proteins and other macromolecules. It can even estimate the extent of    aggregration of biopolymers after reconstitution, without   chromatographic separation.

    Avalanche Photo Diode (APD) Detector

    The   Nicomp 380 can be equipped with various high-powered lasers as well as a   high-gain Avalanche Photo Diode Detector (APD which provides   approximately seven times the gain of a conventional photomultiplier   tube. The APD is used to increase signal-to-noise and sensitivity in   systems that do not scatter light well. Proteins, micelles, other   macro-molecular-based systems, and nanoparticles are often dilute (1   mg/ml or less) and are made of atoms that do not scatter light well. The   Avalanche Photo Diode coupled with a nominally higher powered laser   diode module offers a low cost solution for accurately analyzing   nanoparticles in a short period of time.

    380/MA Multi-angle Goniometer

    Particles   larger than 100 nm do not scatter light isotropically in all   directions. It is possible to make DLS measurements more sensitive to           certain sized particles by changing the angle of detection. The   Nicomp    380 can be equipped with a mini-goniometer that moves the optical fiber   between 12° and 175° by 0.9° increments.

  • 详情请参考Nicomp 380 N3000。点击跳转

  • 详情请参考Nicomp 380 N3000。点击跳转

  • 详情请参考Nicomp 380 N3000。点击跳转

  • 详情请参考Nicomp 380 N3000。点击跳转

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